Synthesis and characterization of poly-5- dimethylaminouridylic acid
66p
I tiakina i:
| Kaituhi matua: | |
|---|---|
| Hōputu: | Thesis |
| Reo: | Ingarihi |
| I whakaputaina: |
Obafemi Awolowo University, Ile Ife, Nigeria
2023
|
| Ngā marau: | |
| Urunga tuihono: | https://ir.oauife.edu.ng/123456789/5242 |
| Tags: |
Tāpirihia he Tūtohu
No Tags, Be the first to tag this record!
|
| _version_ | 1810764576991477760 |
|---|---|
| author | Akindahunsi, Afolabi Akintunde |
| author_facet | Akindahunsi, Afolabi Akintunde |
| author_sort | Akindahunsi, Afolabi Akintunde |
| collection | DSpace |
| description | 66p |
| format | Thesis |
| id | oai:ir.oauife.edu.ng:123456789-5242 |
| institution | My University |
| language | English |
| publishDate | 2023 |
| publisher | Obafemi Awolowo University, Ile Ife, Nigeria |
| record_format | dspace |
| spelling | oai:ir.oauife.edu.ng:123456789-52422023-05-13T18:12:44Z Synthesis and characterization of poly-5- dimethylaminouridylic acid Akindahunsi, Afolabi Akintunde Bromination Polymerization Uridine monophosphate Acid 66p The bromination of uridine monophosphate (UMP) with Br2 in dry formamide gave 5- bromouridine monophosphate (Br5UMP), which by reaction with dimethylamine was converted into 5-dimethylaminouridine monophosphate (Me2N5UMP). This was treated with phosphoric acid by the phosphoromorpholidate method to afford 5-dimethylaminouridine -5'-diphosphate (Me2N5UDP). Poly 5-dimethylaminouridylic acid, otherwise known as Poly (Me2N5U) was prepared by polymerization of 5-dimethylaminouridine diphosphate (Me2N5UDP) with polynucleotide phosphorylase (PNPase). The polymer formed a 1:1 hybrid with polyadenylic acid (Poly A). 2023-05-13T16:28:07Z 2023-05-13T16:28:07Z 1985 Thesis https://ir.oauife.edu.ng/123456789/5242 en application/pdf Obafemi Awolowo University, Ile Ife, Nigeria |
| spellingShingle | Bromination Polymerization Uridine monophosphate Acid Akindahunsi, Afolabi Akintunde Synthesis and characterization of poly-5- dimethylaminouridylic acid |
| title | Synthesis and characterization of poly-5- dimethylaminouridylic acid |
| title_full | Synthesis and characterization of poly-5- dimethylaminouridylic acid |
| title_fullStr | Synthesis and characterization of poly-5- dimethylaminouridylic acid |
| title_full_unstemmed | Synthesis and characterization of poly-5- dimethylaminouridylic acid |
| title_short | Synthesis and characterization of poly-5- dimethylaminouridylic acid |
| title_sort | synthesis and characterization of poly 5 dimethylaminouridylic acid |
| topic | Bromination Polymerization Uridine monophosphate Acid |
| url | https://ir.oauife.edu.ng/123456789/5242 |
| work_keys_str_mv | AT akindahunsiafolabiakintunde synthesisandcharacterizationofpoly5dimethylaminouridylicacid |