HIV prevention clinical trials' community engagement guidelines: inequality, and ethical conflicts.
20p
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| Formato: | Artículo |
| Lenguaje: | inglés |
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Routledge Taylor and Francis group
2023
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| Acceso en línea: | https://ir.oauife.edu.ng/handle/123456789/6348 |
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| _version_ | 1810764577008254976 |
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| author | Folayan, Morenike O Peterson, Kristin |
| author_facet | Folayan, Morenike O Peterson, Kristin |
| author_sort | Folayan, Morenike O |
| collection | DSpace |
| description | 20p |
| format | Article |
| id | oai:ir.oauife.edu.ng:123456789-6348 |
| institution | My University |
| language | English |
| publishDate | 2023 |
| publisher | Routledge Taylor and Francis group |
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| spelling | oai:ir.oauife.edu.ng:123456789-63482023-09-27T03:01:20Z HIV prevention clinical trials' community engagement guidelines: inequality, and ethical conflicts. Folayan, Morenike O Peterson, Kristin Cambodia Cameroon HIV HIV prevention Malawi Nigeria PrEP clinical trials community engagement ethics 20p In 2004 and 2005, the first clinical trials were launched to investigate the use of tenofovir for HIV prevention in Cambodia,Cameroon, Nigeria and Thailand. Controversies erupted over the ethical integrity of the research protocol. We reflect on the events that ledto the controversies and identified that scientific and ethical concerns raised by members of local communities at each of these sites wereerased by trialists, causing crisis that led to premature shut down the early PrEP trials. In the aftermath of these trials, the World HealthOrganisation, UNAIDS, and AVAC developed ethics guidelines intended to recognize the concerns as authentic, and developed guidelines toimprove researchers' engagement of communities in biomedical HIV prevention trial design and implementation. Our findings suggest thatthe ethics guidelines are limited in its ability to address power inequalities that leads to voice erasures and non-recognition of localcompetencies. Rather the ethical documents enabled trialists to gain a new sense of authority through the interpretations of ethical researchconduct enabling trialists regain power that can further entrench inequality and voice erasures. To address concerns with what seems anintractable problem, we suggested models of engagement for off-shored research may be the option. This work was supported by National Science Foundation, Science, Technology and Society, USA [grant number #0829174]. 2023-09-26T16:39:40Z 2023-09-26T16:39:40Z 2020-06-05T00:00:00Z Article Folayan, M. O., & Peterson, K. (2020). HIV prevention clinical trials’ community engagement guidelines: inequality, and ethical conflicts. Global Bioethics, 31(1), 47-66. 32921972 10.1080/11287462.2020.1773061 https://ir.oauife.edu.ng/handle/123456789/6348 en application/pdf Routledge Taylor and Francis group |
| spellingShingle | Cambodia Cameroon HIV HIV prevention Malawi Nigeria PrEP clinical trials community engagement ethics Folayan, Morenike O Peterson, Kristin HIV prevention clinical trials' community engagement guidelines: inequality, and ethical conflicts. |
| title | HIV prevention clinical trials' community engagement guidelines: inequality, and ethical conflicts. |
| title_full | HIV prevention clinical trials' community engagement guidelines: inequality, and ethical conflicts. |
| title_fullStr | HIV prevention clinical trials' community engagement guidelines: inequality, and ethical conflicts. |
| title_full_unstemmed | HIV prevention clinical trials' community engagement guidelines: inequality, and ethical conflicts. |
| title_short | HIV prevention clinical trials' community engagement guidelines: inequality, and ethical conflicts. |
| title_sort | hiv prevention clinical trials community engagement guidelines inequality and ethical conflicts |
| topic | Cambodia Cameroon HIV HIV prevention Malawi Nigeria PrEP clinical trials community engagement ethics |
| url | https://ir.oauife.edu.ng/handle/123456789/6348 |
| work_keys_str_mv | AT folayanmorenikeo hivpreventionclinicaltrialscommunityengagementguidelinesinequalityandethicalconflicts AT petersonkristin hivpreventionclinicaltrialscommunityengagementguidelinesinequalityandethicalconflicts |